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Reading Comprehension

HESI A2

Reading Comprehension

Difficulty: Medium Average Score: 81% Practice

Passage / Scenario

Cystic fibrosis is a disease that is passed down through families. It is caused by a defective gene that makes the body produce abnormally thick and sticky fluid, called mucus. This mucus builds up in the breathing passages of the lungs and in the pancreas. The buildup of mucus results in life-threatening lung infections and serious digestion problems. The disease may also affect the sweat glands and a man's reproductive system. Millions of Americans carry a CF gene, but do not have symptoms. This is because a person with CF must inherit two defective genes, one from each parent. About 1 in 29 Caucasian Americans have the CF gene. It is more common among those of northern or central European descent. Most children with CF are diagnosed by age 2. For a small number, the disease is not detected until age 18 or older. These children often have a milder form of the disease.

In context, the word 'defective' in the first sentence of the passage means which of the following?

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